Article

Chromomycin A <sub>2</sub> potently inhibits glucose-stimulated insulin secretion from pancreatic β cells

2018-06-04

Abstract excerpt

<h4>ABSTRACT</h4> Enhancers or inhibitors of insulin secretion could become therapeutics as well as lead to the identification of requisite β-cell regulatory pathways and increase our understanding of pancreatic islet function. Toward this goal, we previously used an insulin-linked luciferase that is co-secreted with insulin in MIN6 β-cells to perform a high-throughput natural product screen for chronic effects o...

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Literature Corpus work: 3386505f-1628-5368-a77f-0767b28c0b35
DOI: 10.1101/337113

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