Article

Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase

2022-09-27

Abstract excerpt

<h4>Background: </h4> Ours and several studies have reported that, in some cancers, including pancreatic ductal adenocarcinoma (PDAC), the expression of squamous lineage markers, such as esophagus-tissue specific genes, correlated with a poor prognosis. However, the mechanism by which the acquisition of squamous lineage phenotypes leads to a poor prognosis remains unclear. We previously reported that retinoic acid...

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Literature Corpus work: 33450e01-dc3d-584f-a5ef-812e485e3ddc
DOI: 10.21203/rs.3.rs-2084078/v1

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