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Article

Getting everyone to agree on gene signatures for murine macrophage polarization in vitro.

PloS one - 1 Jan 2024

Colombo Giorgia, Pessolano Emanuela, Talmon Maria, Genazzani Armando A, Kunderfranco Paolo

Abstract excerpt

Macrophages, key players in the innate immune system, showcase remarkable adaptability. Derived from monocytes, these phagocytic cells excel in engulfing and digesting pathogens and foreign substances as well as contributing to antigen presentation, initiating and regulating adaptive immunity. Macrophages are highly plastic, and the microenvironment can shaper their phenotype leading to numerous distinct...

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PMID: 38330065
DOI: 10.1371/journal.pone.0297872
PMCID: PMC10852255

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