Article

High-throughput microfluidic micropipette aspiration device to probe time-scale dependent nuclear mechanics in intact cells

2019-05-20

Abstract excerpt

The mechanical properties of the cell nucleus are increasingly recognized as critical in many biological processes. The deformability of the nucleus determines the ability of immune and cancer cells to migrate through tissues and across endothelial cell layers, and changes to the mechanical properties of the nucleus can serve as novel biomarkers in processes such as cancer progression and stem cell differentiation...

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Literature Corpus work: 33372bb5-e7a6-50aa-9d5f-8ad40ef37e93
DOI: 10.1101/641084

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