Article
Real-time viscoelastic deformability cytometry: High-throughput mechanical phenotyping of liquid and solid biopsies.
Science advances - 6 Dec 2024
Asghari Mohammad, Ivetich Sarah Duclos, Aslan Mahmut Kamil, Aramesh Morteza, Melkonyan Oleksandr, Meng Yingchao, Xu Rong, Colombo Monika, Weiss Tobias, Balabanov Stefan, Stavrakis Stavros, deMello Andew J
Abstract excerpt
In principle, the measurement of mechanical property differences between cancer cells and their benign counterparts enables the detection, diagnosis, and classification of diseases. Despite the existence of various mechanophenotyping methods, the ability to perform high-throughput single-cell deformability measurements on liquid and/or solid tissue biopsies remains an unmet challenge within clinical settings. To...
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