Back to search

Article

Pan-cancer spatial characterization of key immune biomarkers in the tumor microenvironment

2025-03-07

Abstract excerpt

<h4>Summary</h4> Deciphering the composition and spatial organization of the tumor immune microenvironment (TiME) is key to uncovering the mechanisms driving cancer progression and treatment response. Spatial biology techniques like multiplex immunofluorescence (mIF) offer detailed insights into the TiME but are often limited to retrospective research studies of individual cancer types. Conversely, bulk omics tec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8095610a-e74f-5dbc-bfa4-4f67390e4013
DOI
10.1101/2025.03.05.641733
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pan-cancer spatial characterization of key immune biomarkers in the tumor microenvironmentDOI 10.1101/2025.03.05.641733
Unveiling spatial complexity in solid tumor immune microenvironments through multiplexed imaging.Semantic proximity
Prognostic significance of spatial immune profiles in human solid cancersSemantic proximity
Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imagingSemantic proximity
The tumor microenvironment across four dimensions: assessing space and time in cancer biologySemantic proximity
A Single-Cell Tumor Immune Atlas for Precision OncologySemantic proximity
Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapySemantic proximity
High-definition spatial transcriptomic profiling of immune cell populations in colorectal cancerSemantic proximity
Single-Cell Analysis of the Pan-Cancer Immune Microenvironment and scTIME PortalSemantic proximity
Spatial omics for profiling the dynamic tumor microenvironmentSemantic proximity
Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphomaSemantic proximity
A review of spatial profiling technologies for characterizing the tumor microenvironment in immuno-oncologySemantic proximity
Topography of cancer-associated immune cells in human solid tumors.Semantic proximity
Select a neighboring publication to make it the new centre.