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Mast cells express IL17A, IL17F and RORC, are activated and persist with IL-17 production in resolved skin of patients with chronic plaque-type psoriasis

2024-02-16

Abstract excerpt

<title>Abstract</title> <p>Little is known about IL-17 expression in psoriasis and the actual cellular source of IL-17 remains incompletely defined. We show that high numbers of IL-17 + mast cells persisted in resolved lesions after treatment (anti-IL-17A, anti-IL-23, UVB or topical dithranol) and correlated inversely with the time span in remission. IL-17 + mast cells were found in T cell-rich areas and often cl...

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Literature Corpus work
32a846d6-c0ab-5bfc-a762-00485a49b95f
DOI
10.21203/rs.3.rs-3958361/v1
Open publication

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Mast cells express IL17A, IL17F and RORC, are activated and persist with IL-17 production in resolved skin of patients with chronic plaque-type psoriasisDOI 10.21203/rs.3.rs-3958361/v1
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