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Article

Deciphering the role of IL17RA in psoriasis and chronic mucocutaneous candidiasis: shared pathways and distinct manifestations.

Frontiers in immunology - 1 Jan 2024

Kadhi Ayat, Eid Edward, Massaad Michel J, El-Rassy Inaam, Khoury Dana Maria, Shimomura Yutaka, Rubeiz Nelly, Kurban Mazen, Nemer Georges

Abstract excerpt

Introduction: Psoriasis and chronic mucocutaneous candidiasis (CMC), although distinct in their clinical manifestations, often coexist within specific patient cohorts. Despite this intriguing clinical observation, their genetic etiologies have been studied separately, neglecting the shared inflammatory mediator, interleukin 17A-F (IL17A-F). Consequently, the immunogenetic foundations underlying these conditions...

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Topics

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Share to Candidiasis, Chronic Mucocutaneous
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Receptors, Interleukin-17

Source

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Identifiers

PMID: 39911581
DOI: 10.3389/fimmu.2024.1516408
PMCID: PMC11796622

Genes

IL17RA
IL17A
IL17RC
IL17RD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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