Article

T helper cell-licensed mast cells promote inflammatory Th17 cells

2021-07-28

Abstract excerpt

<h4>Summary</h4> CD4 + T helper cells (Th) infiltrate sites of inflammation and orchestrate the immune response by instructing local leukocytes. Mast cells (MCs) are tissue sentinel cells particularly abundant in skin and mucosa. Here, we analyzed the interplay between human MCs and Th cells and, through the application of RNAseq and functional assays, showed that Th cells induced a specific transcriptomic progr...

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Literature Corpus work: 25c74992-3c47-515c-bdf2-a895835aa16b
DOI: 10.1101/2021.07.28.454103

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