Article

Allosteric effects of the coupling cation in melibiose transporter MelB

2025-07-15

Abstract excerpt

The major facilitator superfamily (MFS) transporters play significant roles in human health and disease. Salmonella enterica serovar Typhimurium melibiose permease (MelB St ), which catalyzes the symport of galactosides with Na + , H + , or Li + , is a prototype of this important transporter superfamily. We have published the structures of the inward- and outward-facing conformations of MelB St with galactos...

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Literature Corpus work: 329d32b7-ef72-50a7-b014-2bd76a68ff57
DOI: 10.1101/2025.07.10.664195

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