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Article

Substrate recognition and proton coupling by a bacterial member of solute carrier family 17.

The Journal of biological chemistry - 1 May 2023

Batarni Samir, Nayak Nanda, Chang Audrey, Li Fei, Hareendranath Surabhi, Zhou Lexi, Xu Hongfei, Stroud Robert, Eriksen Jacob, Edwards Robert H

Abstract excerpt

The solute carrier 17 family transports diverse organic anions using two distinct modes of coupling to a source of energy. Transporters that package glutamate and nucleotide into secretory vesicles for regulated release by exocytosis are driven by membrane potential but subject to allosteric regulation by H+ and Cl-. Other solute carrier 17 members including the lysosomal sialic acid exporter couple the flux of...

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Identifiers

PMID: 36965620
DOI: 10.1016/j.jbc.2023.104646
PMCID: PMC10149257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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