Article

A method to exploit the structure of genetic ancestry space to enhance case-control studies

2016-03-10

Abstract excerpt

One goal of human genetics is to understand the genetic basis of disease, a challenge for diseases of complex inheritance because risk alleles are few relative to the vast set of benign variants. Risk variants are often sought by association studies in which allele frequencies in cases are contrasted with those from population-based samples used as controls. In an ideal world we would know population-level allele...

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Literature Corpus work: 325c1027-d392-5098-9380-71215b0d823e
DOI: 10.1101/043166

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