Article

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls

2018-02-24

Abstract excerpt

A primary goal of the recent investment in sequencing is to detect novel genetic associations in health and disease improving the development of treatments and playing a critical role in precision medicine. While this investment has resulted in an enormous number of sequenced genomes, individual studies of complex traits are often smaller and underpowered to detect rare variant genetic associations. Existing genet...

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Literature Corpus work: ebcba2a8-8677-5917-ab99-89059fa58afd
DOI: 10.1101/271007

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