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Article

A model-based approach for analysis of spatial structure in genetic data.

Nature genetics - 20 May 2012

Yang Wen-Yun, Novembre John, Eskin Eleazar, Halperin Eran

Abstract excerpt

Characterizing genetic diversity within and between populations has broad applications in studies of human disease and evolution. We propose a new approach, spatial ancestry analysis, for the modeling of genotypes in two- or three-dimensional space. In spatial ancestry analysis (SPA), we explicitly model the spatial distribution of each SNP by assigning an allele frequency as a continuous function in geographic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22610118
DOI: 10.1038/ng.2285
PMCID: PMC3592563

Genes

FOXP2
LCT
OCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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