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Article

A novel test for gene-ancestry interactions in genome-wide association data.

PloS one - 1 Jan 2012

Davies Joanna L, Cazier Jean-Baptiste, Dunlop Malcolm G, Houlston Richard S, Tomlinson Ian P, Holmes Chris C

Abstract excerpt

Genome-wide association study (GWAS) data on a disease are increasingly available from multiple related populations. In this scenario, meta-analyses can improve power to detect homogeneous genetic associations, but if there exist ancestry-specific effects, via interactions on genetic background or with a causal effect that co-varies with genetic background, then these will typically be obscured. To address this...

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Identifiers

PMID: 23236349
DOI: 10.1371/journal.pone.0048687
PMCID: PMC3516524

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CYBRD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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