Article

SEMA5A-PLXNB3 axis promotes PDAC liver metastasis outgrowth through enhancing Warburg effect

2022-01-27

Abstract excerpt

<h4>Background: </h4> Patients bearing liver metastasis of pancreatic adeno carcinoma (PDAC) suffer from poor prognosis due to its short duration and high mortality. Complex tumor microenvironment (TME) exists in liver metastatic niches and tumor associated macrophages (TAMs) have play vital roles in metastasis generation and outgrowth. <h4>Methods: </h4>: We set off from investigating the aggregation and infiltra...

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Literature Corpus work: 3252b298-7557-5b2d-b4f4-47918a20c692
DOI: 10.21203/rs.3.rs-1260906/v1

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