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Ancient DNA reveals that few GWAS loci have been strongly selected during recent human history

2021-04-14

Abstract excerpt

Genetic data from ancient humans has provided new evidence in the study of loci thought to be under historic selection, and thus is a powerful tool for identifying instances of selection that might be missed by methods that use present-day samples alone. Using a curated set of disease-associated variants from the NHGRI-EBI GWAS Catalog, we provide an analysis to identify disease-associated variants that bear signa...

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Literature Corpus work
322402f4-3785-50c8-8802-076d3946b682
DOI
10.1101/2021.04.13.439742
Open publication

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Ancient DNA reveals that few GWAS loci have been strongly selected during recent human historyDOI 10.1101/2021.04.13.439742
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