Article
Ancient DNA reveals pervasive directional selection across West Eurasia.
Nature - 1 Jun 2026
Akbari Ali, Perry Annabel, Barton Alison R, Kariminejad Mohammadreza, Gazal Steven, Li Zheng, Zeng Yating, Mittnik Alissa, Patterson Nick, Mah Matthew, Zhou Xiang, Price Alkes L, Lander Eric S, Pinhasi Ron, Rohland Nadin, Mallick Swapan, Reich David
Abstract excerpt
Ancient DNA has transformed our understanding of population history1, but its potential to reveal as much about human evolutionary biology has not been realized because of limited sample sizes and the difficulty of distinguishing sustained rises in allele frequency increasing fitness-directional selection-from shifts due to migrations, population structure, or non-adaptive purifying or stabilizing selection2-7....
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