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Article

Genome-wide scans for footprints of natural selection.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 12 Jan 2010

Oleksyk Taras K, Smith Michael W, O'Brien Stephen J

Abstract excerpt

Detecting recent selected 'genomic footprints' applies directly to the discovery of disease genes and in the imputation of the formative events that molded modern population genetic structure. The imprints of historic selection/adaptation episodes left in human and animal genomes allow one to interpret modern and ancestral gene origins and modifications. Current approaches to reveal selected regions applied in...

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Identifiers

PMID: 20008396
DOI: 10.1098/rstb.2009.0219
PMCID: PMC2842710

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