Article

Asgard ESCRT-III and VPS4 reveal evolutionary conserved chromatin binding properties of the ESCRT machinery

2021-11-29

Abstract excerpt

<h4>ABSTRACT</h4> The ESCRT machinery drive membrane remodeling in numerous processes in eukaryotes. Genes encoding for ESCRT proteins have been identified in Asgard archaea, a newly discovered superphylum, currently recognized as the ancestor of all eukaryotes. This begs the question of the functional evolutionary origin of this machinery and its conservation across lineages. Here, we find that Asgard-ESCRT’s ex...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 320ddc6f-8769-572e-babe-c7dcb49a6c1f
DOI: 10.1101/2021.11.29.470303

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Asgard ESCRT-III and VPS4 reveal evolutionary conserved chromatin binding properties of the ESCRT machineryDOI 10.1101/2021.11.29.470303Read

The ESCRT protein CHMP5 promotes T cell leukemia by controlling BRD4-p300-dependent transcriptionSemantic proximity Read

3D Chromatin Architecture Remodeling during Human Cardiomyocyte Differentiation Reveals A Role Of HERV-H In Demarcating Chromatin DomainsSemantic proximity Read

Human Satellite 3 DNA encodes megabase-scale transcription factor binding platformsSemantic proximity Read

Multi-omics Analysis of Dsup Expressing Human Cells Reveals Open Chromatin Architectural Dynamics Underyling RadioprotectionSemantic proximity Read

Resetting the yeast epigenome with human nucleosomesSemantic proximity Read

A systematic analysis of human CHMP protein interactions: Additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complexSemantic proximity Read

Virus-induced paraspeckle-like condensates are essential hubs for gene expression and their formation drives genomic instabilitySemantic proximity Read

Differential role for VPS4 isoforms in cytokinetic abscission confers a regulatory function for monomeric VPS4A and VTA1 in mammalian cellsSemantic proximity Read

Transcription factors interact with RNA to regulate genesSemantic proximity Read

Identification and characterization of a human MORC2 DNA binding region that is required for gene silencingSemantic proximity Read

Genome-wide identification and characterisation of HOT regions in the human genomeSemantic proximity Read

PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencingSemantic proximity Read