Article

High-dimensional profiling of pediatric immune responses to solid organ transplantation

2022-08-18

Abstract excerpt

Solid organ transplant remains a life-saving therapy for children with end-stage heart, lung, liver, or kidney disease; however, ∼25% of allograft recipients experience acute rejection within the first 12 months after transplant. Our ability to detect rejection early and to develop less toxic immunosuppressive agents is hampered by an incomplete understanding of the immune changes associated with rejection, partic...

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Literature Corpus work: 31f8bbbc-ed2f-53c2-96c1-ce590b299027
DOI: 10.1101/2022.08.17.22278895

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