Article

Inhibition of K63 ubiquitination by G-Protein pathway suppressor 2 (GPS2) regulates mitochondria-associated translation

2022-07-05

Abstract excerpt

<title>Abstract</title> <p>G-Protein Pathway Suppressor 2 (GPS2) is an inhibitor of non-proteolytic K63 ubiquitination mediated by the E2 ubiquitin-conjugating enzyme Ubc13. Previous studies have associated GPS2-mediated restriction of ubiquitination with the regulation of insulin signaling, inflammatory responses and mitochondria-nuclear communication across different tissues and cell types. However, a detailed...

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Literature Corpus work: 31f73a2e-f7c9-58a1-8d99-db71437d329b
DOI: 10.21203/rs.3.rs-1772179/v1

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