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ZBTB7A interferes with the RPL5‐P53 feedback loop and reduces endoplasmic reticulum stress‐induced apoptosis of pancreatic cancer cells

19 Jun 2024

Abstract excerpt

Endoplasmic reticulum (ER) stress is a primary mechanism leading to cell apoptosis, making it of great research interests in cancer management. This study delves into the function of ribosomal protein L5 (RPL5) in ER stress within pancreatic cancer (PCa) cells and investigates its regulatory mechanisms. Bioinformatics predictions pinpointed RPL5 as an ER stress-related gene exhibiting diminished expression in...

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PMID: 38896079
DOI: 10.1002/mc.23772

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