Article

Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation

2021-07-28

Abstract excerpt

<h4>ABSTRACT</h4> G-Protein Pathway Suppressor 2 (GPS2) was recently identified as an endogenous inhibitor of non-proteolytic ubiquitination mediated by the E2 ubiquitin-conjugating enzyme Ubc13. GPS2-mediated restriction of K63 ubiquitination is associated with the regulation of insulin signaling, inflammation and mitochondria-nuclear communication, however a detailed understanding of the targets of GPS2/Ubc13 a...

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Literature Corpus work: 5e49d2a2-b054-57b7-b62b-9176b5b396ad
DOI: 10.1101/2021.07.28.454107

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