Article

AI-enabled Spatial Profiling of Circulating Tumor-Immune Ecosystems Predicts Patient Outcomes Across Cancers

2026-07-03

Abstract excerpt

Circulating tumor cells (CTCs) and immune cells form dynamic multicellular ecosystems in blood, but their spatial organization and clinical relevance have not been systematically characterized. We developed the Cell and Cluster Identification Program (CCIP), an artificial intelligence–based framework that analyzes routine multiplex immunofluorescence blood scans to segment cells, identify CTCs and five immune line...

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Literature Corpus work: c1e942fc-3a9a-5df8-b979-1d7dbc92fdc3
DOI: 10.64898/2026.07.02.736133

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