Article

Inflammatory and interferon gene expression signatures in patients with mitochondrial disease

2023-02-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> People with mitochondrial disease (MtD) are susceptible to metabolic decompensation and neurological symptom progression in response to an infection. Increasing evidence suggests that mitochondrial dysfunction may cause chronic inflammation, which may promote hyperresponsiveness to pathogens and neurodegeneration. <bold>Methods:</bold> We collected whole blood f...

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Literature Corpus work: 31ebfe15-c346-589e-8a4a-f4f08e05c64e
DOI: 10.21203/rs.3.rs-2612547/v1

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