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Cell Death and Inflammation: The Role of Mitochondria in Health and Disease

3 Mar 2021

Abstract excerpt

Mitochondria serve as a hub for a multitude of vital cellular processes. To ensure an efficient deployment of mitochondrial tasks, organelle homeostasis needs to be preserved. Mitochondrial quality control (MQC) mechanisms (i.e., mitochondrial dynamics, biogenesis, proteostasis, and autophagy) are in place to safeguard organelle integrity and functionality. Defective MQC has been reported in several conditions...

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PMID: 33802550
DOI: 10.3390/cells10030537

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