Article

Transcriptional Profiling of Leukocytes in Critically Ill COVID19 Patients: Implications for Interferon Response and Coagulation

2020-11-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> COVID19 is caused by the SARS-CoV-2 virus and has been associated with severe inflammation leading to organ dysfunction and mortality. Our aim was to profile the transcriptome in leukocytes from critically ill patients positive for COVID19 compared to those negative for COVID19 to better understand the COVID19 associated host response. For these studies, all pat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 30586138-6093-5016-8db8-8ba896e1af07
DOI: 10.21203/rs.3.rs-63632/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Profiling of Leukocytes in Critically Ill COVID19 Patients: Implications for Interferon Response and CoagulationDOI 10.21203/rs.3.rs-63632/v2Read

Transcriptomic clustering of critically ill COVID-19 patientsSemantic proximity Read

Comprehensive Transcriptomic Analysis of COVID-19 Blood, Lung, and AirwaySemantic proximity Read

Identification of PBMC-based molecular signature associational with COVID-19 disease severitySemantic proximity Read

Comprehensive transcriptomic analysis of COVID-19 blood, lung, and airwaySemantic proximity Read

Longitudinal peripheral blood transcriptional analysis of COVID-19 patients captures disease progression and reveals potential biomarkersSemantic proximity Read

Transcriptomic clustering of critically ill COVID-19 patientsSemantic proximity Read

Transcriptomic Similarities and Differences in Host Response between SARS-CoV-2 and Other Viral InfectionsSemantic proximity Read

Dysregulated transcriptional responses to SARS-CoV-2 in the peripherySemantic proximity Read

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approachesSemantic proximity Read

Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected PatientsSemantic proximity Read

Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in bloodSemantic proximity Read

People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burdenSemantic proximity Read