Article

Pharmacogenetic manipulation of Locus coeruleus activity in monkeys demonstrates its role in cognitive effort

2026-07-27

Abstract excerpt

The noradrenergic nucleus locus coeruleus (LC) is involved in numerous cognitive functions. Its activation often enhances sensory and motor performance and its activity correlates with arousal, which altogether suggest a general role in the mobilization of resources for cognition and action. We recently showed its strong and specific implication in physical effort and indirect evidence suggest that it might also b...

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Literature Corpus work: 316be806-3f18-5ebe-8983-942e37c101a8
DOI: 10.64898/2026.07.23.740243

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