Article
Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin.
Brain research - 15 Jun 2016
Weinshenker David, Holmes Philip V
Abstract excerpt
Decades of research confirm that noradrenergic locus coeruleus (LC) neurons are essential for arousal, attention, motivation, and stress responses. While most studies on LC transmission focused unsurprisingly on norepinephrine (NE), adrenergic signaling cannot account for all the consequences of LC activation. Galanin coexists with NE in the vast majority of LC neurons, yet the precise function of this...
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