Article

A streamlined workflow for long-read DNA methylation analysis with NanoMethViz and Bioconductor

2025-02-24

Abstract excerpt

Long-read sequencing technologies have transformed the field of epigenetics by enabling direct, single-base resolution detection of DNA modifications, such as methylation. This produces novel opportunities for studying the role of DNA methylation in gene regulation, imprinting, and disease. However, the unique characteristics of long-read data, including the modBAM format and extended read lengths, necessitate the...

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Literature Corpus work: 31682466-dfae-59c4-b81e-f964ea9af2b2
DOI: 10.12688/f1000research.155204.2

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