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<i>DMRscaler</i> : A Scale-Aware Method to Identify Regions of Differential DNA Methylation Spanning Basepair to Multi-Megabase Features

2021-02-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Pathogenic mutations in genes that control chromatin function have been implicated in rare genetic syndromes. These chromatin modifiers exhibit extraordinary diversity in the scale of the epigenetic changes they affect, from single basepair modifications by DNMT1 to whole genome structural changes by PRM1/2. Patterns of DNA methylation are related to a diverse set of epigene...

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Literature Corpus work: 55b966e7-8ea8-57b3-9fec-f438f23cf785
DOI: 10.1101/2021.02.03.428187

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