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Article

Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA).

BMC genomics - 15 Jun 2018

Richard Albert Julien, Koike Tasuku, Younesy Hamid, Thompson Richard, Bogutz Aaron B, Karimi Mohammad M, Lorincz Matthew C

Abstract excerpt

BACKGROUND: Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and specific histone modifications, the interplay between transcription and these epigenetic marks at allelic resolution is typically not investigated genome-wide due to a lack of...

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PMID: 29907088
DOI: 10.1186/s12864-018-4835-2
PMCID: PMC6003194

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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