Article

Bacillus Calmette-Guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation

2014-06-03

Abstract excerpt

Patients with chronic granulomatous disease (CGD) lack generation of reactive oxygen species (ROS) through the phagocyte NADPH oxidase NOX2. CGD is an immune deficiency that leads to frequent infections with certain pathogens; this is well documented for S. aureus and A. fumigatus , but less clear for mycobacteria. We therefore performed an extensive literature search which yielded 297 cases of CGD patients with...

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Literature Corpus work: 31469278-19d9-591c-83fd-027e47eb9bc0
DOI: 10.1101/005835

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