Article
Chronic granulomatous disease: the solving of a clinical riddle at the molecular level.
Clinical immunology and immunopathology - 1 Jun 1993
Curnutte J T
Abstract excerpt
Chronic granulomatous disease is an uncommon inherited disorder of phagocytes in which the defective production of microbicidal oxidants leads to an enhanced susceptibility to bacterial and fungal infections. Despite the near uniform absence of the respiratory burst in CGD phagocytes, there is a striking clinical and genetic heterogeneity in this disorder. The recent elucidation of the molecular basis of CGD now...
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