Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide determinants of mortality and motor progression in Parkinson’s disease

7 Jun 2024

Abstract excerpt

There are 90 independent genome-wide significant genetic risk variants for Parkinson's disease (PD) but currently only five nominated loci for PD progression. The biology of PD progression is likely to be of central importance in defining mechanisms that can be used to develop new treatments. We studied 6766 PD patients, over 15,340 visits with a mean follow-up of between 4.2 and 15.7 years and carried out...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lysosomal Storage Disorders Research
Share to Parkinson's Disease Mechanisms and Treatments
Share to Studies on Chitinases and Chitosanases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38849413
DOI: 10.1038/s41531-024-00729-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide determinants of mortality and motor progression in Parkinson’s diseasePMID 38849413Read ↗

Genome-wide determinants of mortality and motor progression in Parkinson’s diseaseSemantic proximity Read ↗

Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease.Semantic proximity Read ↗

Genome-wide Analysis of Motor Progression in Parkinson DiseaseSemantic proximity Read ↗

Genome-wide association study of Parkinson’s disease progression biomarkers in 12 longitudinal patients’ cohortsSemantic proximity Read ↗

Genome-wide association studies of cognitive and motor progression in Parkinson's diseaseSemantic proximity Read ↗

Genetic risk of Parkinson disease and progression:Semantic proximity Read ↗

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.Semantic proximity Read ↗

Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression.Semantic proximity Read ↗

Baseline genetic associations in the Parkinson's Progression Markers Initiative (PPMI).Semantic proximity Read ↗

Parkinson’s Disease motor and non-motor progression models emerge from pathway-level transcriptomicsSemantic proximity Read ↗

Genetic Associations With Rapid Motor and Cognitive Deterioration in Parkinson’s DiseaseSemantic proximity Read ↗

Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.