Article

Administration of the glutamate-modulating drug riluzole after stress reverses its delayed effects on the amygdala

2023-03-10

Abstract excerpt

Extracellular glutamate levels are elevated across brain regions immediately after stress. Despite sharing common features in their genesis, the patterns of stress-induced plasticity that eventually take shape are strikingly different between these brain areas. While stress impairs structure and function in the hippocampus, it has the opposite effect on the amygdala. Riluzole, an FDA-approved drug known to modulat...

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Literature Corpus work: 3120619f-a820-5690-af01-1d0340ef04c3
DOI: 10.1101/2023.03.08.531819

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