Article

Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress

2020-07-01

Abstract excerpt

Exposure to prolonged stress is a major risk-factor for psychiatric disorders such as generalized anxiety and major depressive disorder (MDD). Human imaging studies have identified structural and functional abnormalities in the prefrontal cortex of MDD patients, particularly Brodmann’s area 25 (BA25). Further, deep brain stimulation of BA25 reduces symptoms of treatment-resistant depression. The rat homolog of BA2...

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Literature Corpus work: 64038e2a-bc84-56e6-a188-1c942e08338a
DOI: 10.1101/2020.06.30.181115

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