Article

Antibodies to native gluten arise from cross-reactive B cells with implications for epitope spreading in celiac disease

2022-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Antibodies to deamidated gluten peptides are accurate diagnostic markers of celiac disease (CeD). However, antibody binding to all possible gluten epitopes has not previously been investigated. To map antibody reactivity in detail and to understand the connection between disease-relevant B-cell and T-cell epitopes, we took advantage of a high-density peptide array for assessment of serum antibod...

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Literature Corpus work: 30da27d3-dda8-58be-8be6-2927a4553364
DOI: 10.1101/2022.01.29.478298

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