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Article

Genomic landscape of pathogenic mutation of APC, KRAS, TP53, PIK3CA, and MLH1 in Indonesian colorectal cancer.

PloS one - 1 Jan 2022

Marbun Vania Myralda Giamour, Erlina Linda, Lalisang Toar Jean Maurice

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) needs several mutations to occur in various genes, and can vary widely in different individuals; hence it is essential to be discovered in a specific population. Until recently, there has been no known study describing APC, TP53, PIK3CA, KRAS, and MLH1 of CRC in Indonesian population. This study describes the nature and location of mutation in CRC patients treated at three...

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PMID: 35709138
DOI: 10.1371/journal.pone.0267090
PMCID: PMC9202917

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