Article

From individual to population disease risk: population-averaged polygenic risk scores

2022-06-23

Abstract excerpt

Polygenic risk score (PRS) is a tool to quantify the susceptibility of an individual to a disease by using the results of individual gene sequencing to calculate the cumulative effect of genetic susceptibility loci. In this study, we extend the individual-based PRS to the population-based mean polygenic risk score (PMPRS), Further more, we constructed the risk score ratio (RSR) for etiology exploration. In the cas...

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Literature Corpus work: 30aa9021-8422-5f9d-9d24-a5db9807f89f
DOI: 10.1101/2022.06.20.22276484

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