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Article

Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases.

Nature human behaviour - 1 Sept 2024

Abstract excerpt

Understanding the interactions between genetic risk and lifestyles on different types and age onsets of cardiovascular disease (CVD) risk can help identify individuals for whom lifestyle changes would be beneficial. Here we developed three polygenic risk scores, called MetaPRSs, for coronary artery disease, ischaemic stroke and intracerebral haemorrhage by combining PRSs for CVD and CVD-related risk factors in...

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Identifiers

PMID: 38987358
DOI: 10.1038/s41562-024-01923-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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