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Article

Identification of susceptible genes for complex chronic diseases based on disease risk functional SNPs and interaction networks.

Journal of biomedical informatics - 1 Oct 2017

Li Wan, Zhu Lina, Huang Hao, He Yuehan, Lv Junjie, Li Weimin, Chen Lina, He Weiming

Abstract excerpt

Complex chronic diseases are caused by the effects of genetic and environmental factors. Single nucleotide polymorphisms (SNPs), one common type of genetic variations, played vital roles in diseases. We hypothesized that disease risk functional SNPs in coding regions and protein interaction network modules were more likely to contribute to the identification of disease susceptible genes for complex chronic...

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PMID: 28927989
DOI: 10.1016/j.jbi.2017.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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