Article

MRI Elastography Identifies Regions of Extracellular Matrix Reorganization Associated with Shorter Survival in Glioblastoma Patients

2022-11-13

Abstract excerpt

<h4>Background</h4> The biomechanical tissue properties of glioblastoma tumors are heterogeneous, but the molecular mechanisms involved and the biological implications are poorly understood. Here, we combine magnetic resonance elastography (MRE) measurement of tissue stiffness with RNA sequencing of tissue biopsies to explore the molecular characteristics of the stiffness signal. <h4>Methods</h4> MRE was performed...

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Literature Corpus work: 305f0dda-6e67-5009-b82c-85428732cdee
DOI: 10.1101/2022.11.07.22282021

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