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Article

Identification of Prognostic Genes in Gliomas Based on Increased Microenvironment Stiffness

27 Jul 2022

Abstract excerpt

With a median survival time of 15 months, glioblastoma multiforme is one of the most aggressive primary brain cancers. The crucial roles played by the extracellular matrix (ECM) stiffness in glioma progression and treatment resistance have been reported in numerous studies. However, the association between ECM-stiffness-regulated genes and the prognosis of glioma patients remains to be explored. Thus, using...

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PMID: 35954323
DOI: 10.3390/cancers14153659

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