Article
Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme.
PloS one - 1 Jan 2011
Zinn Pascal O, Mahajan Bhanu, Majadan Bhanu, Sathyan Pratheesh, Singh Sanjay K, Majumder Sadhan, Jolesz Ferenc A, Colen Rivka R
Abstract excerpt
BACKGROUND: Despite recent discoveries of new molecular targets and pathways, the search for an effective therapy for Glioblastoma Multiforme (GBM) continues. A newly emerged field, radiogenomics, links gene expression profiles with MRI phenotypes. MRI-FLAIR is a noninvasive diagnostic modality and was previously found to correlate with cellular invasion in GBM. Thus, our radiogenomic screen has the potential to...
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