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Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke.

2023-02-15

Abstract excerpt

<title>Abstract</title> <p>Microglia are key mediators of inflammatory responses within the brain, as they regulate pro-inflammatory responses while also limiting neuroinflammation via reparative phagocytosis. Thus, identifying genes that modulate microglial function may reveal novel therapeutic interventions for promoting better outcomes in diseases featuring extensive inflammation, such as stroke. To facilitate...

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Literature Corpus work
5cd48963-290e-59e1-8d6e-eb3ad44f9db3
DOI
10.21203/rs.3.rs-2557290/v1
Open publication

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Single-cell analysis identifies Ifi27l2a as a novel gene regulator of microglial inflammation in the context of aging and stroke.DOI 10.21203/rs.3.rs-2557290/v1
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