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Article

Irradiation induces glioblastoma cell senescence and senescence-associated secretory phenotype.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2016

Jeon Hee-Young, Kim Jun-Kyum, Ham Seok Won, Oh Se-Yeong, Kim Jaebong, Park Jae-Bong, Lee Jae-Yong, Kim Sung-Chan, Kim Hyunggee

Abstract excerpt

Glioblastoma multiforme (GBM) is one of the most aggressive and fatal primary brain tumors in humans. The standard therapy for the treatment of GBM is surgical resection, followed by radiotherapy and/or chemotherapy. However, the frequency of tumor recurrence in GBM patients is very high, and the survival rate remains poor. Delineating the mechanisms of GBM recurrence is essential for therapeutic advances. Here,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26586398
DOI: 10.1007/s13277-015-4439-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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