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Plasma extracellular vesicle sampling from high grade gliomas demonstrates a small RNA signature indicative of disease and identifies lncRNA RPPH1 as a high grade glioma biomarker.

2024-08-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>High grade gliomas (HGGs) and cells of the tumour microenvironment (TME) secrete extracellular vesicles(EVs) into the plasma that contain genetic and protein cargo, which function in paracrine signaling. Isolation of these EVs and their cargo from plasma could lead to a simplistic tool that can inform on diagnosis and disease course of HGG. <bold>Methods: </bold...

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Literature Corpus work: f874c5a2-f4a7-527d-b01e-ab594c72e797
DOI: 10.21203/rs.3.rs-4693910/v1

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