Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression.

Journal of advanced research - 1 Nov 2025

Chen Shengcai, Zhou Zhimin, Ye Yangchen, You Zhen, Lv Qi, Dong Yu, Luo Jindan, Gong Liang, Zhu Yanfen

Abstract excerpt

INTRODUCTION: Extrachromosomal circular DNA (eccDNA) plays significant roles in cancer progression and prognosis. However, it remains unclear whether cell-free eccDNA, considered more stable than linear DNA, possesses cancer-specific genomic features. Furthermore, the biogenesis and function of eccDNAs are not yet fully understood. OBJECTIVES: This study aims to characterize the genomic landscape of urinary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell-Free Nucleic Acids

Share to Disease Progression

Share to DNA Breaks, Double-Stranded

Share to Genomic Instability

Share to Prognosis

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 39875054
DOI: 10.1016/j.jare.2025.01.039
PMCID: PMC12627897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The urinary eccDNA landscape in prostate cancer reveals associations with genome instability and vital roles in cancer progression.PMID 39875054Read ↗

Cell free extrachromosomal circular DNA is common in human urineSemantic proximity Read ↗

Extrachromosomal circular DNA: biogenesis, structure, functions and diseasesSemantic proximity Read ↗

Extrachromosomal circular DNA orchestrates genome heterogeneity in urothelial bladder carcinoma.Semantic proximity Read ↗

Extrachromosomal Circular DNA Orchestrates Genome Heterogeneity and Outcome in Urothelial Bladder CarcinomaSemantic proximity Read ↗

EccBase: A high-quality database for exploration and characterization of extrachromosomal circular DNAs in cancerSemantic proximity Read ↗

Classification of extrachromosomal circular DNA with a focus on the role of extrachromosomal DNA (ecDNA) in tumor heterogeneity and progressionSemantic proximity Read ↗

scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cellsSemantic proximity Read ↗

Molecular characterization of cell-free eccDNAs in human plasmaSemantic proximity Read ↗

Sub-nucleosomal organization in urine cell-free DNASemantic proximity Read ↗

eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancersSemantic proximity Read ↗

Extrachromosomal circular DNA in cancer: history, current knowledge, and methodsSemantic proximity Read ↗

Extrachromosomal circular DNA (eccDNA): an emerging star in cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.